Well-defined diimine copper(I) complexes as catalysts in click azide-alkyne cycloaddition reactions.
نویسندگان
چکیده
A series of 1,4-disubstituted 1,2,3-triazoles have been prepared in high yields while respecting the stringent Click criteria. In these reactions, highly stable pre-formed complexes bearing diimine ligands were used.
منابع مشابه
Highly active copper-catalysts for azide-alkyne cycloaddition.
Bis-triphenylphosphano complexes of copper(I)-carboxylates serve as efficient catalysts for azide-alkyne cycloaddition. The triazole formation takes place straightforwardly at ambient temperature providing a wide variety of products with good yields in the presence of 0.005-0.05% catalyst.
متن کاملAdvancements in the mechanistic understanding of the copper-catalyzed azide–alkyne cycloaddition
The copper-catalyzed azide-alkyne cycloaddition (CuAAC) is one of the most broadly applicable and easy-to-handle reactions in the arsenal of organic chemistry. However, the mechanistic understanding of this reaction has lagged behind the plethora of its applications for a long time. As reagent mixtures of copper salts and additives are commonly used in CuAAC reactions, the structure of the cata...
متن کاملCarbon-rich "Click" 1,2,3-triazoles: hexaphenylbenzene and hexa-peri-hexabenzocoronene-based ligands for Suzuki-Miyaura catalysts.
Hexaphenylbenzene (HPB) and hexa-peri-hexabenzocoronene-(HBC) functionalised 1,2,3-triazoles have been synthesised using an optimised copper(i)-catalysed azide-alkyne cycloaddition (CuAAC) reaction. The coordination chemistry of these ligands was explored through the synthesis of the respective palladium(ii) complexes and their activity as catalysts in the Suzuki-Miyaura reaction assessed.
متن کاملCopper(I)–Phosphinite Complexes in Click Cycloadditions: Three‐Component Reactions and Preparation of 5‐Iodotriazoles
The remarkable activity displayed by copper(I)-phosphinite complexes of general formula [CuBr(L)] in two challenging cycloadditions is reported: a) the one-pot azidonation/cycloaddition of boronic acids, NaN3, and terminal alkynes; b) the cycloaddition of azides and iodoalkynes. These air-stable catalysts led to very good results in both cases and the expected triazoles could be isolated in pur...
متن کاملFULL PAPER Copper(I)‒Phosphinite Complexes in Click Cycloadditions: Three- Component Reactions and Preparation of 5-Iodotriazoles
The remarkable activity displayed by copper(I)phosphinite complexes of general formula [CuBr(L)] in two challenging cycloadditions is reported: a) the one pot azidonation/cycloaddition from boronic acids, NaN3 and terminal alkynes; b) the cycloaddition of azides and iodoalkynes. These airstable catalysts led to very good results in both cases and the expected triazoles could be isolated pure un...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Molecules
دوره 18 8 شماره
صفحات -
تاریخ انتشار 2013